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Presentations, Publications, New Applications Identified


 

1)    Garrett CT. Molecular Diagnostics and Genomics, Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, September 12, 2002.

2)    Garrett CT.  Functional Genomics - a  Medical Perspective. Virginia Biotechnology Summit, McLean, VA, October 16, 2002

3)    Cassel JB and Garrett CT. Clinical Informatics and Genomics. (with Dr. JB Cassel), Virginia Biotechnology Summit, McLean, VA, October 16, 2002.

4)    Dumur, C.I., Dechsukhum, C., Garrett, C.T., Wilkinson, D.S., Ferreira-Gonzalez, A.  Genome wide detection of loss of heterozygosity (LOH) in microdissected prostate cancer paraffin-embedded tissues using Affymetrix HuSNP microarrays. J Molecular Diagnostics, 4:252, 2002.

5)    Dumur, C.I., Dechsukhum, C., Garrett, C.T., Wilkinson, D.S., Ferreira-Gonzalez, A.  Genome-wide detection of LOH in prostate cancer using human SNP microarray technology. Genomics, 81:260-269, 2003.

6)    Dumur, C.I., Best, A., Garrett, C.T., Nasim, S., Wilkinson, D.S., Ferreira-Gonzalez, A.  Quality control and quality assurance in microarray data analysis. J Molecular Diagnostics, 4:253, 2002.

7)    Garrett, C.T., Dumur, C.I., Nasim, S., Wilkinson, D.S., Ferreira-Gonzalez A.  Assessing methods of calculating expression values in microarray data analysis. J Molecular Diagnostics, 4:257, 2002.

8)    Miller, WG. Lab Automation 2003, Palm Springs, CA, February 2003, “The LIS as an integral part of the clinical EMR, impact on evidence based medicine.”

9)    Archer, KJ. Expression summaries for oligonucleotide arrays: implications for multiple hypothesis testing. College of William and Mary, Department of Mathematics Applied Mathematics Colloquim, March 24, 2003.

10)   Ginder, GD, Massey Cancer Center. NIH CaBIG Site Visit Review Panel, Massey Cancer Center, Richmond, VA, September 8, 2003.

11)   Penberthy, L, Overview of Bioinformatics at the Massey Cancer Center. NIH CaBIG Site Visit Review Panel, Massey Cancer Center, Richmond, VA, September 8, 2003.

12)   Wellons, M & Liu, J, Clinical Research Database, NIH CaBIG Site Visit Review Panel, Massey Cancer Center, Richmond, VA, September 8, 2003

13)   Cassel, JB, Massey Cancer Center Information System (MCCIS). NIH CaBIG Site Visit Review Panel, Massey Cancer Center, Richmond, VA, September 8, 2003.

14)   Garrett, CT, CTRF Cancer Genomics Project. NIH CaBIG Site Visit Review Panel, Massey Cancer Center, Richmond, VA, September 8, 2003.

15)   Miller, G, Pathology Integrated Clinical Research Database. NIH CaBIG Site Visit Review Panel, Massey Cancer Center, Richmond, VA, September 8, 2003.

16)   Miller, WG.  Athena Society Conference, Samos, Greece, September 2003, on Trends and Issues Facing Laboratory Medicine; session title “Informatics – How to Keep Track Of, and Do Something With All The Data”

17)   Lee JK, Laudeman T, Kanter J, James T, Siadaty MS, Prorock A, Gallagher P, Bao Y, Fox JW, Freeman B, Puiu D, Witten TM, Davis JM, Wen LM, Mallonee D, Alves JM, Buck GA, Schlauch K, Weller J, Stewart J, Mangalam H, Knaus WA, Spraggins T. GeneX Va: VBC gene expression database and analysis system for multiple users in clinical research, submitted to Nucleic Acids.

18)   Van Everdink WJ, Baranova A, Lummen C, Tyazhelova T, Looman MWG, Ivanov D, Verlind E, Pestova A, Faber H, van der Veen AY, Yankovsky N, Vellenga E, Buys CHCM. “RFP2, c13ORF1 and FAM10A4 are the most likely tumor suppressor gene candidates for B-cell chronic lymphocytic leukemia” Cancer Genetics and Cytogenetics, in press. CGC 6699

19)   Vajirapinyo, V., Al-Timimi, A., Gorreta, F., Del Giacco, L., Grant, G.M., Jamison, C., Chandhoke, V., Marcus, N.A. and Born, T.L. "Microarray Gene Expression Analysis of Cultured Human Normal and Osteoarthritic Chondrocytes" American Academy of Orthopaedic Surgeons Meeting, March 10-14, 2004, San Francisco, California

20)   Gorreta F., Del Giacco L., Schlauch K., VanMeter A., Grant G., Christensen A., Chandhoke V., Goodman Z., Younoszai A, Elariny, H., Ong J., Younossi ZM.  “Gender Differences in Hepatic Gene Expression of Patients with Non-Alcoholic Steatohepatitis (NASH)” American Association for Study of Liver Disease, October 2003 (Submitted) Boston, Massachusetts

21)   Mehrota A., Goodman Z., Elariny H., Younoszai A., Bopari N., Assmann J., Chandhoke V., Younossi, ZM.  “The Utility of Immunostaining for Mallory Bodies in Non-Alcoholic Fatty Liver Disease (NAFLD)” American Association for Study of Liver Disease, October 2003 (Submitted) Boston, Massachusetts

22)   Miller K., Born T., Ong J., Younoszai A., Elariny H., Schlauch K., Goodman Z., Younossi, ZM. “Proteomics of Non-Alcoholic Steatohepatitis (NASH): Analysis of Protein Expression Profiles Using SELDI-TOF Mass Spectrometry” American Association for Study of Liver Disease, October 2003 (Submitted) Boston, Massachusetts

23)   Baranova A., Ivanov D., Tyazhelova T., Alsheddi T., Gorreta F., Schlauch S., Pestova A., Skoblov M., Nikitin E., Yankovsky N., Chandhoke V. “New candidate genes involved in progression of human B-cell chronic lymphocytic leukemia revealed by positional cloning and microarray-based approaches” FASEB Summer Research Conference -Hematological malignancies, July 26-31, 2003, Saxton Rivers, Vermont

24)   Born, T., Ong, J., Schlauch, K., Elariny, H., Younoszai, A., Goodman, Z., Christensen, A., Assman, J., Chandhoke, V., and Younossi, Z.M. “Insulin Resistance, Serum Leptin and Fibrosis in Non-alcoholic Fatty Liver Disease (NAFL)” Digestive Disease Week, May 2003, Orlando, Florida

25)   Ong J, Schlauch K., Del Giacco L., Gorretta F., Grant G., Elariny H., Younoszai A., Goodman Z., Christensen A., Chandhoke V., Younossi ZM. “The Impact of Insulin-Resistance on the Genomics of Non-alcoholic Fatty Liver Diseases (NAFL).” Digestive Disease Week. May 2003, Orlando, Florida

26)   Schlauch K., Ong J., Del Giacco L., Goretta F., Grant G., Elariny H., Younoszai A., Goodman Z., Christensen A., Chandhoke V., Younossi ZM.  “The Impact of Anti-diabetic Medications on the Gene Expressions of Diabetics with Non-alcoholic Fatty Liver Disease (NAFL).” Digestive Disease Week. May 2003, Orlando, Florida

27)   Born, T., Ong, J., Schlauch, K., Elariny, H., Younoszai, A., Goodman, Z., Christensen, A., Assman, J., Chandhoke, V., and Younossi, Z.M. “Insulin Resistance, Serum leptin, and Fibrosis in Non-alcoholic Fatty Liver Disease (NAFL)” Digestive Disease Week, May 24-29 2003, Orlando, Florida

28)   Yankovsky NK, Ivanov DV, Tyazhelova TV, Pestova AA, Skoblov M, Baranova A. “Human genes RFP2, RFP2OS, KCNRG and C13ORF1 as a new candidates for TSG deleted in 13q14 area.” Human Genome Meeting, April 27-30, 2003, Cancun, Mexico

29)   Ivanov DV, Tyazhelova TV, Lemonnier L, Kononenko N, Pestova AA, Prevarskaya N, Skryma R, Panchin YV, Yankovsky NK, Baranova AV. “A new human gene KCNRG encoding potassium channel regulating protein is a cancer suppressor gene candidate located in 13q14.3” FEBS Letters, March 27, 2003, 539(1-3): 156-60

30)   Schlauch K., Grant G., Ong J., Chandhoke V., Christensen A., Younossi, ZM. “A Genomic Study of Non-alcoholic Fatty Liver Disease. Informatics” Microarray Data Analysis Conference, February 2003, Zurich, Switzerland

31)   Gorreta F., Al-Timimi A., Del Giacco L., Gasparian A., Chebotaev D., Sakharova O., Kondratieva T., Geraymovych L., Lobashev A., Kisselev F., Grant G., Jamison D.C., Baranova A., Soyfer V., Chandhoke V. “A study of genes differentially expressed in breast cancer samples of different histology and different stages of disease.” Genomics and Proteomics Advances in Cancer Research Meeting, February 10-12, 2003, Bethesda, Maryland

32)   Baranova A., Lobashev D., Ivanov D., Kroukovskaya L., Yankovsky N., Kozlov A. “Discovering of human cancer-related genes by EST cluster-sorting approach.” The 52nd Annual Meeting of the American Society of Human Genetics, October 15-19, 2002, Baltimore, Maryland

33)   Grant, G. DNA miroarrays in cancer, presented at Biotechnology, Cancer & Drug Resistance, New Targets, New Dioagnostics & New Treatments for Tumors Resistant to Current Therapies, July 7th/8th 2003, Dublin, Ireland.

1)    Karen Kurdziel, submitted 6/13/02 a response to RFP-NIH-27018 “Early Clinical Trials of Imaging Agents”.  (This contract will permit the VCU Molecular Imaging Center to respond to subsequent specific RFPs for development of new imaging agents.  30 million dollars has been set aside to support applications in this programmatic area.  Tissue acquisition and molecular diagnostic testing form critical components of the application.), total amount "approved" for disbursement is $2,245,168 Total award (Direct + Indirect) over the 5-years (Sept 2002-2007) Status Funded

2)    Gordon Ginder, Lung Cancer Gene Expression Molecular Genetics Project, 7/1/02 -  6/30/04, $409,700 Status Funded

3)    Carleton Garrett, MD, PhD, “Using Molecular Genetics to Target 'High Risk' Youth Smokers”, 7/1/03 – 12/31/03, $50,000 Status Funded.

4)    Anthony Guiseppi-Elie, Genomic Classification of Primary Brain Tumors and Development of Diagnostic Biochips 01/01/04-12/31/07 - $200,000 Status Unfunded.

5)    Peter O’Connell, Clinical and Molecular Measurements Predicting Optimal Breast Cancer Therapies $2,000,000 Status Pending

6)    Andrew Yeudall, Site-dependent gene expression and oral cancer outcome, 7/1/04-6/30/09,  $250,000/yr ($1,250,000 dc) Status Pending

7)    Lynne Penberthy/Greg Miller, caBIG Initiative – 3 subprojects submitted for total direct cost $500,000 for one year. Status Pending

8)    Curtis Jamison, A Virtual Data Warehouse for Microarray Data, NIH, $350,000, Status Unfunded

9)    Curtis Jamison, Clustering with Knowledge for Gene Expression Data, NIH, $450,000, Status Pending

10)   Kellie J. Archer, Exploration and identification of novel methodologies for image analysis and probe set expression summaries for oligonucleotide microarrays. American Cancer Society Institutional Research Grant. 06/01/2003 – 06/30/2004, $2844 Status Funded.

11)   Vikas Chandhoke, Novel therapeutic and prophylactic modalities to protect U.S. armed forces against major threat agents. DOD. 2003-2005. $1.42M Status Funded.

12)   Vikas Chandhoke, HIV research, Acambis 2003, $325,000, Status Funded.

13)   Ken Alibek,  Chronic Viral Infection and Tumorigenesis of Mammary Gland, CDMRP, Status Pending.

14)   Ken Alibek,  Multiple Chronic Viral Infections Induce Prostate Cancer, CDMRP, Status Pending.

15)   Ancha Baranova, Human KCNRG Gene Suppressing K+ Channel Activity as a Putative Tumor Suppressor Gene for Prostate Carcinoma, CDMRP, Status Pending